How SLE is diagnosed
SLE is diagnosed?
SLE is difficult to diagnose.
It frequently resembles other forms of aching disease
such as rheumatoid arthritis.
Diagnosis can take several months or even a few years.
Normally people are referred by their GP to a rheumatologist
otherwise kidney specialist who will make the ultimate
The test most normally used is the Anti-Nudear Antibody
(ANA) test. Nevertheless, even though this test is
positive in over 90 per cent of people with SLE, it
can as well be present in other rheumatic conditions
plus sometimes in healthy individuals. Prior to a
definite analysis is made, the individual's whole
health picture plus symptoms should be taken into
consideration. X-rays or perhaps a skin ,Other blood
tests or kidney biopsy may be taken to assist diagnosis.
To make a diagnosis of SLE, an individual must illustrate
clinical proof of a multi-system disease (i.e. has
shown abnormalities in a number of different organ
systems). The following are distinctive manifestations
which may lead to suspicion of SLE.
butterfly rash; hair loss ulcers in the mouth.
pain; redness along with swelling.
unusual urinanalysis symptomatic of kidney disease.
Lining membranes: pericarditis ; pleurisy plus peritonitis
(takentogether this kind of swelling is known aspolyserositis).
hemolytic anemia the red cells are shattered by autoantibodies
leukopenia low down white blood cell count; thrombocytopenia
infiltrates that is fleeting.
psychosis; convulsions; nerve abnormalities that grounds
strange sensations or else alter muscular control or
If an individual has numerous
of these symptoms, the physician will then generally
order a series of tests to inspect the functioning of
the individual's resistant system. In common, physicians
appearance for evidence of autoantibodies.
Lab Tests will
help to Diagnose Lupus
Laboratory testing in Systemic Lupus Erythematosus
(SLE) plays a several important roles in making a diagnosis,
to observe the activity of the disease, monitoring effect
to treatment, as well as detecting side effects of medications.
This assessment of common laboratory testing in SLE
will summarize the lab tests most generally ordered
via your rheumatologist as well as how these tests are
interpreted. Since there is no precise test for SLE,
your doctor has to rely on a number of different issues
to make a diagnosis including history, physical exam
as well as laboratory data. The laboratory information
therefore plays an important role.
EVALUATION in Systemic Lupus Erythematosus
1. General Tests
Leukocyte Count Tests
Platelet Count Tests
Creatinine/Blood Chemistry tests
Plasma Proteins tests
Erythrocyte Sedimentation Rate tests
C-Reactive Protein tests
Blood Glucose tests
2. Immune Testing
anti-Ro (SS-A) Tests
anti-La (SS-B) Tests
Lupus Anticoagulant Tests
Anti-Cardiolipan Antibody Tests
Beta-2 Glycoprotein I Tests