Tuesday, March 11, 2008
Healthy people can benefit from a blood test which measures an enzyme called myeloperoxidase. "Being able to identify those who are at-risk to have coronary artery diseases and be at-risk to have heart attacks is really the majority of the battle," according to Dr. Stanley Hazen, the developer of the MPO blood test. Secreted by the white blood cells, MPO signals inflammation. It releases bleach like substance which damages the cardiovascular system. More than a decade ago, Hazen connected heart attacks in people with existing heart problems to MPO. New studies suggested MPO might be a predictive marker for heart diseases in healthier people. Physicians like George Gabriel are intrigued by the findings. "If you had top levels of MPO, which was the same risk of having an event as if you had high LDL cholesterol," said Gabriel. The six year study of more than 3,000 people at the age of 40 and older showed MPO levels were much higher in healthy people who later developed heart disease or had a heart attack. But were those levels the cause or effect?
"That's the question," Gabriel said. "That's something which needs to be evaluated further." Hazen said the findings might help determine who benefits from an MPO screening test. Yarbrough said he'd take the test if it becomes available. Hazen is confident of his MPO blood test. He had reportedly filed for patents on MPO as a biomarker for cardiovascular diseases. He believes this test will be primarily for those people who don't know they may be at risk for a heart attack.
posted by emedinfo
@ 4:22 AM
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